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Article

Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle.

The EMBO journal - 15 Sept 1997

Li F N, Johnston M

Abstract excerpt

Grr1 protein of the yeast Saccharomyces cerevisiae is a central component of a glucose signal transduction mechanism responsible for glucose-induced gene expression. It is required for glucose-stimulated regulation of Rgt1, a repressor of several glucose-induced HXT genes. Grr1 also plays a role in regulating the cell cycle, because it is required for degradation of the G1 cyclins Cln1 and Cln2. We discovered...

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Identifiers

PMID: 9312022
DOI: 10.1093/emboj/16.18.5629
PMCID: PMC1170195

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