Bladder cancer risk from the perspective of genetic polymorphisms in the carcinogen metabolizing enzymes.

Abstract excerpt

Urinary bladder cancer is a socially significant healthcare problem. A diverse array of aromatic and heterocyclic amines, derived from the chemical and transport industry, diet, and cigarette smoke are considered carcinogens for the bladder. To exert their carcinogenic effect and to initiate the carcinogenic response, the arylamines require a metabolic activation by the host enzymes to chemically reactive...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Acetyltransferases
• Share to NAT2 gene