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Article

Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer

1 Feb 2006

Abstract excerpt

A homozygous deletion of the DOCK8 (dedicator of cytokinesis 8) locus at chromosome 9p24 was found in a lung cancer cell line by array-CGH analysis. Cloning of the full-length DOCK8 cDNA led us to define that the DOCK8 gene encodes a protein consisting of 2,099 amino acids. DOCK8 was expressed in a variety of human organs, including the lungs, and was also expressed in type II alveolar, bronchiolar epithelial and...

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PMID: 16391785
DOI: 10.3892/ijo.28.2.321

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