Article
Parameters of LRP5 from a structural and molecular perspective.
Critical reviews in eukaryotic gene expression - 1 Jan 2005
Johnson Mark L, Summerfield Douglas T
Abstract excerpt
LRP5, along with LRP6 and their Drosophila homolog, Arrow, constitute a novel subclass of the LDL receptor superfamily. The arrangement of structural motifs in these receptors is different from the other members of the superfamily, and only recently have we begun to understand the functional importance of human LRP5 (and LRP6). Whole genome positional cloning studies have identified a number of mutations in LRP5...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
