Article
Multiple sclerosis in G: genes and geography.
Clinical neurology and neurosurgery - 1 Mar 2006
Tienari Pentti, Bonetti Alessandro, Pihlaja Hannele, Saastamoinen Kari-Pekka, Rantamäki Terhi
Abstract excerpt
Multiple sclerosis (MS) shows uneven geographic distribution globally as well as within countries. In epidemiological studies we have previously demonstrated that there is a high-risk focus for MS in the southern Ostrobothnian region of western Finland. In genetic studies we recently identified haplotypes that associate with MS specifically in patients originating from southern Ostrobothnia suggesting a founder...
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