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Article

Contribution of common risk variants to multiple sclerosis in Orkney and Shetland.

European journal of human genetics : EJHG - 1 Nov 2021

Barnes Catriona L K, Hayward Caroline, Porteous David J, Campbell Harry, Joshi Peter K, Wilson James F

Abstract excerpt

Orkney and Shetland, the population isolates that make up the Northern Isles of Scotland, are of particular interest to multiple sclerosis (MS) research. While MS prevalence is high in Scotland, Orkney has the highest global prevalence, higher than more northerly Shetland. Many hypotheses for the excess of MS cases in Orkney have been investigated, including vitamin D deficiency and homozygosity: neither was...

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Identifiers

PMID: 34088990
DOI: 10.1038/s41431-021-00914-w
PMCID: PMC8560837

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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