Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acute asthma in children: Relationships among CD14 and CC16 genotypes, plasma levels, and severity.

American journal of respiratory and critical care medicine - 15 Mar 2006

Martin Andrew C, Laing Ingrid A, Khoo Siew-Kim, Zhang Guicheng, Rueter Kristina, Teoh Laurel, Taheri Shahir, Hayden Catherine M, Geelhoed Gary C, Goldblatt Jack, LeSouëf Peter N

Abstract excerpt

RATIONALE: The majority of previous studies investigating asthma genetics have focused on cohorts with stable disease and have not defined mechanisms important during acute asthma. CD14 and CC16 each play a key role in biologically important inflammatory pathways and the gene of each has a functional promoter-region polymorphism. OBJECTIVES: This study was designed to determine the influence of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Asthma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers

Share to Enzyme-Linked Immunosorbent Assay

Share to Lipopolysaccharide Receptors

Share to Prognosis

Share to Severity of Illness Index

Share to Uteroglobin

Source

Identifiers

PMID: 16387800
DOI: 10.1164/rccm.200509-1367OC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acute asthma in children: Relationships among CD14 and CC16 genotypes, plasma levels, and severity.PMID 16387800Read ↗

TNF-alpha (-308 G/A) and CD14 (-159T/C) polymorphisms in the bronchial responsiveness of Korean children with asthma.Semantic proximity Read ↗

Association of CD14 C159T polymorphism with atopic asthma susceptibility in children from Southeastern China: a case-control study.Semantic proximity Read ↗

The effect of CD14 C159T polymorphism on in vitro IgE synthesis and cytokine production by PBMC from children with asthma.Semantic proximity Read ↗

Association between CD14 polymorphisms and serum soluble CD14 levels: effect of atopy and endotoxin inhalation.Semantic proximity Read ↗

Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma SeveritySemantic proximity Read ↗

CD14 gene polymorphism is not associated with asthma but rather with bronchial obstruction and hyperreactivity in Slovenian children with non-atopic asthma.Semantic proximity Read ↗

Association of CD14 -159 (-260C/T) polymorphism and asthma risk: an updated genetic meta-analysis study.Semantic proximity Read ↗

Association of CD14 -260 (-159) C>T and asthma: a systematic review and meta-analysis.Semantic proximity Read ↗

Clara cell protein 16 (CC16) gene polymorphism influences the degree of airway responsiveness in asthmatic children.Semantic proximity Read ↗

Association of TGF-beta1, CD14, IL-4, IL-4R and ADAM33 gene polymorphisms with asthma severity in children and adolescents.Semantic proximity Read ↗

The effect of CD14-c159T genotypes on the cytokine response to endotoxin by peripheral blood mononuclear cells from asthmatic children.Semantic proximity Read ↗

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.