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Article

Clara cell protein 16 (CC16) gene polymorphism influences the degree of airway responsiveness in asthmatic children.

The Journal of allergy and clinical immunology - 1 Mar 2003

Sengler Claudia, Heinzmann Andrea, Jerkic Silvija-Pera, Haider Assia, Sommerfeld Christine, Niggemann Bodo, Lau Susanne, Forster Johannes, Schuster Antje, Kamin Wolfgang, Bauer Carl, Laing Ingrid, LeSouef Peter, Wahn Ulrich, Deichmann Klaus, Nickel Renate

Abstract excerpt

BACKGROUND: Several studies have indicated linkage of chromosome 11q12-13 to asthma and associated traits. Among other candidate genes, the Clara cell protein 16 (CC16) gene maps to this region. CC16 is expressed in the bronchial epithelium and exhibits potent anti-inflammatory properties. A single-nucleotide polymorphism (SNP) in the CC16 gene (A38G) was previously associated with asthma. OBJECTIVE: We evaluated...

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Identifiers

PMID: 12642831
DOI: 10.1067/mai.2003.180

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FEV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clara cell protein 16 (CC16) gene polymorphism influences the degree of airway responsiveness in asthmatic children.PMID 12642831Read ↗

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