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Article

Considerable haplotype diversity within the 23kb encompassing the ADH7 gene.

Alcoholism, clinical and experimental research - 1 Dec 2005

Han Yi, Oota Hiroki, Osier Michael V, Pakstis Andrew J, Speed William C, Odunsi Adekunle, Okonofua Friday, Kajuna Sylvester L B, Karoma Nganyirwa J, Kungulilo Selemani, Grigorenko Elena, Zhukova Olga V, Bonne-Tamir Batsheva, Lu Ru-B, Parnas Josef, Schulz Leslie O, Kidd Judith R, Kidd Kenneth K

Abstract excerpt

BACKGROUND: Of the seven known human alcohol dehydrogenase (ADH) genes, the non-liver expressed ADH7 gene codes for the enzyme with the highest maximal activity for ethanol. Previous study from our laboratory has suggested that ADH7 has an epistatic role for protection against alcoholism based on a single ADH7 SNP. METHODS: We have now studied seven SNPs, additional populations for the SNP previously examined,...

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Source

Identifiers

PMID: 16385178
DOI: 10.1097/01.alc.0000191769.92667.04

Genes

ADH7

Provenance

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Related research

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Research trail→

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Considerable haplotype diversity within the 23kb encompassing the ADH7 gene.PMID 16385178Read ↗

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