Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Possible epistatic role of ADH7 in the protection against alcoholism.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2004

Osier M V, Lu R-B, Pakstis A J, Kidd J R, Huang S-Y, Kidd Kenneth K

Abstract excerpt

In recent studies of the role of the alcohol dehydrogenase genes (ADH) in alcoholism the ADH1B Arg47His polymorphism appears to affect risk via a protective effect associated with the ADH1B*47His. Here we present evidence for an additional effect from outside the Class I ADH genes, presumably fro...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Dehydrogenase
Share to Alcoholism
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Introns

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 15048643
DOI: 10.1002/ajmg.b.20136

Genes

ADH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15048643-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible epistatic role of ADH7 in the protection against alcoholism.PMID 15048643Read ↗

Scanning of genetic effects of alcohol metabolism gene (ADH1B and ADH1C) polymorphisms on the risk of alcoholism.Semantic proximity Read ↗

Considerable haplotype diversity within the 23kb encompassing the ADH7 gene.Semantic proximity Read ↗

Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism.Semantic proximity Read ↗

Mechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model.Semantic proximity Read ↗

Protective variant associated with alcohol dependence in a Mexican American cohort.Semantic proximity Read ↗

Genetic variants in or near ADH1B and ADH1C affect susceptibility to alcohol dependence in a British and Irish population.Semantic proximity Read ↗

Evidence of positive selection on a class I ADH locus.Semantic proximity Read ↗

Identification of new single nucleotid polymorphisms (SNP) in alcohol dehydrogenase class IV ADH7 gene within a French population.Semantic proximity Read ↗

A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity.Semantic proximity Read ↗

Single-nucleotide polymorphisms interact to affect ADH7 transcription.Semantic proximity Read ↗

Ethnic related selection for an ADH Class I variant within East Asia.Semantic proximity Read ↗

Variation in the ADH1B proximal promoter affects expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.