Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism.

doi:10.1093/hmg/ddm295

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Article

Association of the gastric alcohol dehydrogenase gene ADH7 with variation in alcohol metabolism.

Human molecular genetics - 15 Jan 2008

Birley Andrew J, James Michael R, Dickson Peter A, Montgomery Grant W, Heath Andrew C, Whitfield John B, Martin Nicholas G

Abstract excerpt

Seven alcohol-metabolizing enzymes are encoded by the human alcohol dehydrogenase (ADH) gene cluster on chromosome 4q22-23. One of these genes, ADH7, is uniquely expressed in the stomach mucosa and can influence metabolism of alcohol before its absorption into the blood. However, the contribution of ADH7 to the overall genetic variation in alcohol oxidation in vivo is unknown. Data on in vivo alcohol metabolism...

Topics

Adolescent
Adult
Alcohol Dehydrogenase
Ethanol
Humans
Introns
Linkage Disequilibrium
Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 17921519
DOI: 10.1093/hmg/ddm295

Genes

ADH7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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