Article
Phenotypic switching in Cryptococcus neoformans.
Microbiology (Reading, England) - 1 Jan 2006
Guerrero A, Jain N, Goldman D L, Fries B C
Abstract excerpt
Phenotypic switching has been described in serotype A and D strains of Cryptococcus neoformans. It occurs in vivo during chronic infection and is associated with differential gene expression and changes in virulence. The switch involves changes in the polysaccharide capsule and cell wall that affect the yeast's ability to resist phagocytosis. In addition, the phenotypic switch variants elicit qualitatively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
