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Article

Cryptococcus neoformans variants generated by phenotypic switching differ in virulence through effects on macrophage activation.

Infection and immunity - 1 Mar 2010

Guerrero A, Jain N, Wang X, Fries B C

Abstract excerpt

Macrophages have a central role in the pathogenesis of cryptococcosis since they are an important line of defense, serve as a site for fungal replication, and also can contribute to tissue damage. The objective of this study was to investigate the interaction of macrophages with cells from smooth-colony variants (SM) and mucoid-colony variants (MC) arising from phenotypic switching of Cryptococcus neoformans....

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Identifiers

PMID: 20048044
DOI: 10.1128/IAI.01049-09
PMCID: PMC2825907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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