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Article

Phenotypic switching and its implications for the pathogenesis of Cryptococcus neoformans.

FEMS yeast research - 1 Jun 2006

Jain Neena, Guerrero Abraham, Fries Bettina C

Abstract excerpt

Phenotypic switching has been described in several strains of Cryptococcus neoformans. It occurs in vivo during chronic infection and is associated with differential gene expression and changes in virulence. The switch involves changes in the polysaccharide capsule and cell wall that affect the yeast's ability to resist phagocytosis. In addition, the phenotypic switch variants elicit qualitatively different...

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Identifiers

PMID: 16696644
DOI: 10.1111/j.1567-1364.2006.00039.x
PMCID: PMC2745630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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