Article
Phenotypic switching in Cryptococcus neoformans.
Microbes and infection - 1 Nov 2002
Fries Bettina C, Goldman David L, Casadevall Arturo
Abstract excerpt
Cryptococcus neoformans strains exhibit considerable phenotype variability with regards to the capsular polysaccharide, sterol composition of the cell wall, and cell and colony morphology. Phenotypic changes can occur spontaneously during in vitro passage of strains or during chronic infection in vivo and may be associated with differences in virulence. Studies from our laboratory have demonstrated that phenotype...
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