Article
Phenotypic switching in Candida tropicalis: association with modification of putative virulence attributes and antifungal drug sensitivity.
Medical mycology - 1 Jan 2014
Moralez Alane T P, França Emanuele J G, Furlaneto-Maia Luciana, Quesada Regina M B, Furlaneto Marcia C
Abstract excerpt
Although Candida tropicalis has become an increasingly important human pathogen, little is known regarding its potential to cause disease. In this study we evaluated the phenotypic switching ability of C. tropicalis and analyzed the effect of switching on biological properties related to virulence factors. We demonstrated that C. tropicalis switched spontaneously, reversibly and at high frequency (10(-1) to...
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