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Article

Phenotypic switching of Cryptococcus neoformans can influence the outcome of the human immune response.

Cellular microbiology - 1 Aug 2003

Pietrella Donatella, Fries Bettina, Lupo Patrizia, Bistoni Francesco, Casadevall Arturo, Vecchiarelli Anna

Abstract excerpt

The human pathogenic fungus Cryptococcus neoformans exhibits the phenomenon of phenotypic switching, a process that generates variant colonies that can differ in morphology, virulence and other characteristics such as capsular glucuronoxylomannan (GXM) size and structure. A previous study established that mucoid colony (MC) variants of C. neoformans were more virulent and elicited a different inflammatory...

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PMID: 12864811
DOI: 10.1046/j.1462-5822.2003.00297.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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