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Article

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

The Journal of cell biology - 2 Jan 2006

Relaix Frédéric, Montarras Didier, Zaffran Stéphane, Gayraud-Morel Barbara, Rocancourt Didier, Tajbakhsh Shahragim, Mansouri Ahmed, Cumano Ana, Buckingham Margaret

Abstract excerpt

The growth and repair of skeletal muscle after birth depends on satellite cells that are characterized by the expression of Pax7. We show that Pax3, the paralogue of Pax7, is also present in both quiescent and activated satellite cells in many skeletal muscles. Dominant-negative forms of both Pax3 and -7 repress MyoD, but do not interfere with the expression of the other myogenic determination factor, Myf5,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16380438
DOI: 10.1083/jcb.200508044
PMCID: PMC2063537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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