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Article

Pax7 directs postnatal renewal and propagation of myogenic satellite cells but not their specification.

The EMBO journal - 18 Aug 2004

Oustanina Svetlana, Hause Gerd, Braun Thomas

Abstract excerpt

The paired-box transcription factor Pax7 has been claimed to specify the muscle stem cell lineage since inactivation of Pax7 led to a failure to detect muscle satellite cells. Here we show that muscles of juvenile Pax7(-/-) mice at P11 contain a reduced but substantial number of satellite cells. Neither juvenile nor adult Pax7(-/-) mice displayed a significant reduction in the number and size of myotubes,...

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Share to Muscle Development
Share to MyoD Protein
Share to Myogenic Regulatory Factor 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Satellite Cells, Skeletal Muscle

Source

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Identifiers

PMID: 15282552
DOI: 10.1038/sj.emboj.7600346
PMCID: PMC514519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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