Article
Noncoding variant in the complement factor H gene and risk of exudative age-related macular degeneration in a Chinese population.
Investigative ophthalmology & visual science - 1 Feb 2010
Cui Lei, Zhou Haiying, Yu Jie, Sun Erdan, Zhang Yinbo, Jia Wei, Jiao Yiqun, Snellingen Torkel, Liu Xipu, Lim Apiradee, Wang Ningli, Liu Ningpu
Abstract excerpt
PURPOSE: To investigate whether the previously reported noncoding variant of the complement factor H (CFH) gene and two coding variants of the complement component 3 (C3) gene are associated with exudative age-related macular degeneration (AMD) in Chinese patients. METHODS: One hundred fifty Chinese patients with exudative AMD and 161 control individuals without AMD were recruited for the study. Genomic DNA was...
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