Article
Determination of somatic mutant frequencies at glycophorin A and T-cell receptor loci for biodosimetry of acute and prolonged irradiation.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine - 1 May 2000
Saenko A S, Zamulaeva I A, Smirnova S G, Orlova N V, Selivanova E I, Matveeva N P, Kaplan M A, Nugis V Y, Nadezhina N M, Tsyb A F
Abstract excerpt
Somatic mutant frequencies at glycophorin A (GPA) and T-cell receptor (TCR) loci were assessed. The dependence of the GPA mutant frequency on doses of acute and prolonged irradiation was shown. In the case of acute irradiation the GPA mutant frequency displayed a three-fold greater dose-related increase as compared to prolonged irradiation. A dose-dependent increase in the TCR variant frequency was found only in...
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