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Article

Genetic predisposition to sporadic cancer: how to handle major effects of minor genes?

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2005

Fijneman Remond J A

Abstract excerpt

Predisposition to non-familial, sporadic cancer is strongly influenced by multiple tumor susceptibility genes (TSGs), each with apparently minor effects on the cancer phenotype. Sequence analysis of the human genome has yielded numerous single nucleotide polymorphisms (SNPs), raising the expectation that new low-penetrance TSGs will be identified that can be used to estimate an individuals cancer risk. However,...

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Identifiers

PMID: 16373962
DOI: 10.1155/2005/737191
PMCID: PMC4615169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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