Article
Relationships between familial risks of cancer and the effects of heritable genes and their SNP variants.
Mutation research - 30 Dec 2005
Hemminki Kari, Bermejo Justo Lorenzo
Abstract excerpt
Familial risks for cancer can be used in many ways in guiding gene identification efforts and, more broadly, in understanding cancer etiology. Gene identification efforts may be properly designed and targeted if the familial risks are well characterized and the mode of inheritance is identified. Single nucleotide polymorphisms (SNPs) are extensively used in case-control studies of practically all cancer types....
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