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Article

Molecular pathogenesis of sporadic colorectal cancers.

Chinese journal of cancer - 6 Jan 2016

Yamagishi Hidetsugu, Kuroda Hajime, Imai Yasuo, Hiraishi Hideyuki

Abstract excerpt

Colorectal cancer (CRC) results from the progressive accumulation of genetic and epigenetic alterations that lead to the transformation of normal colonic mucosa to adenocarcinoma. Approximately 75% of CRCs are sporadic and occur in people without genetic predisposition or family history of CRC. During the past two decades, sporadic CRCs were classified into three major groups according to frequently...

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Identifiers

PMID: 26738600
DOI: 10.1186/s40880-015-0066-y
PMCID: PMC4704376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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