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Article

N-cadherin-mediated cell motility requires cis dimers.

Cell communication & adhesion - 1 Jan 2000

Kim Young J, Johnson Keith R, Wheelock Margaret J

Abstract excerpt

Cadherins are expressed on the cell surface as a dimer in the membrane of one cell (cis dimer) that interacts with a cis dimer on an adjacent cell to form an adhesive trans dimer. It is well established that both cis and trans dimers must form for the cadherin to be an effective adhesion protein. In addition to their adhesive activity cadherins also play an important role in modulating cell behavior by regulating...

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Identifiers

PMID: 16371344
DOI: 10.1080/15419060500305971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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