Article
Lateral clustering of cadherin-4 without homophilic interaction: possible involvement in the concentration process at cell-cell adhesion sites as well as in the cell adhesion activity.
Biochemical and biophysical research communications - 5 Oct 2000
Murase S, Hirano S, Wang X, Kitagawa M, Natori M, Taketani S, Suzuki S T
Abstract excerpt
It is thought that the concentration of classic cadherins at cell-cell adhesion sites is essential for generating strong cell-cell adhesion activity, but the mechanism is not well understood. To clarify the structural basis of the concentration process and the cell adhesion activity, we constructed various mutants of cadherin-4 and examined the adhesion properties of the transfectants. A deletion mutant lacking...
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