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Article

Association of tumor necrosis factor gene polymorphisms and prolonged mechanical ventilation after coronary artery bypass surgery.

Critical care medicine - 1 Jan 2003

Yende Sachin, Quasney Michael W, Tolley Elizabeth, Zhang Qing, Wunderink Richard G

Abstract excerpt

OBJECTIVE: Prolonged mechanical ventilation is a common complication after coronary artery bypass graft surgery. Tumor necrosis factor alpha is an important proinflammatory mediator in the post-coronary artery bypass graft inflammatory cascade. We attempted to study the effect of polymorphisms at the -308 site in the promoter region of the tumor necrosis factor gene (TNF-308) and the +250 site within the...

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PMID: 12545006
DOI: 10.1097/00003246-200301000-00021

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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