Article
Bi-directional regulation of postsynaptic cortactin distribution by BDNF and NMDA receptor activity.
The European journal of neuroscience - 1 Dec 2005
Iki Junko, Inoue Akihiro, Bito Haruhiko, Okabe Shigeo
Abstract excerpt
Abstract Cortactin is an F-actin-associated protein which interacts with the postsynaptic scaffolding protein Shank at the SH3 domain and is localized within the dendritic spine in the mouse neuron. Green fluorescent protein (GFP)-based time-lapse imaging revealed cortactin redistribution from dendritic cytoplasm to postsynaptic sites by application of brain-derived neurotrophic factor (BDNF). This response was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
