Article
Src controls neuronal migration by regulating the activity of FAK and cofilin.
Neuroscience - 30 Apr 2015
Wang J T, Song L Z, Li L L, Zhang W, Chai X J, An L, Chen S L, Frotscher M, Zhao S T
Abstract excerpt
Migration of postmitotic neurons in the developing cortex along radial glial fiber is essential for the formation of cortical layers. Several neurological diseases are caused by defects in neuronal migration, underlining the importance of this process for brain function. Multiple molecules are involved in this process. However, the precise mechanisms are largely unknown. In the present study, we examined the...
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