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Article

A dynamin-3 spliced variant modulates the actin/cortactin-dependent morphogenesis of dendritic spines.

Journal of cell science - 15 Mar 2005

Gray Noah W, Kruchten Anne E, Chen Jing, McNiven Mark A

Abstract excerpt

Immature dendrites extend many actin-rich filopodial structures that can be replaced by synapse-containing dendritic spines as the neuron matures. The large GTPase dynamin-3 (Dyn3) is a component of the postsynapse in hippocampal neurons but its function is undefined. Here, we demonstrate that a specific Dyn3 variant (Dyn3baa) promotes the formation of immature dendritic filopodia in cultured neurons. This effect...

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Identifiers

PMID: 15741233
DOI: 10.1242/jcs.01711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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