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Article

Transient suppression of cortactin ectopically induces large telencephalic neurons towards a GABAergic phenotype.

Journal of cell science - 1 Sept 2000

Cheng Y, Leung S, Mangoura D

Abstract excerpt

Excitatory and inhibitory neuronal cell fates require specific expression of both neurotransmitter and morphological phenotypes. The role of the F-actin cytoskeleton in morphological phenotypes has been well documented, but its role in neurotransmitter phenotype expression remains unknown. Here we present evidence that the F-actin binding protein cortactin participates in determining both aspects of cell fate in...

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PMID: 10954415
DOI: 10.1242/jcs.113.18.3161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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