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Article

ALOX5 promoter genotype, asthma severity and LTC production by eosinophils.

Allergy - 1 Jan 2006

Kalayci O, Birben E, Sackesen C, Keskin O, Tahan F, Wechsler M E, Civelek E, Soyer O U, Adalioglu G, Tuncer A, Israel E, Lilly C

Abstract excerpt

BACKGROUND: The number of Sp1-Egr1 binding tandem repeats at the ALOX5 promoter influences gene transcription and may modify the response to anti-leukotriene treatment. The relationship of ALOX5 variants to asthma severity and leukotriene production by eosinophils is unknown. OBJECTIVE: To characterize ALOX5 mRNA expression and cysteinyl-leukotriene production by eosinophils from individuals bearing ALOX5...

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Source

Identifiers

PMID: 16364163
DOI: 10.1111/j.1398-9995.2006.00979.x

Genes

ALOX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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