Article
Selecting stable molecular targets for treatment and prevention of AIDS.
Genome informatics. International Conference on Genome Informatics - 1 Jan 2005
Wang Yaoyu E, Zhang Chao, Berzofsky Jay, DeLisi Charles
Abstract excerpt
The common consideration in approaching protection against HIV, whether by a vaccine or therapeutic, is identification of suitable targets. Among the central criteria for suitability is target stability; i.e. resistance to mutation. In this paper we address the problem of stability, and develop methods for identifying stable targets. The targets that we focus on are structures formed by viral peptides and...
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