Article
Prediction of well-conserved HIV-1 ligands using a matrix-based algorithm, EpiMatrix.
Vaccine - 1 Nov 1998
Schafer J R, Jesdale B M, George J A, Kouttab N M, De Groot A S
Abstract excerpt
This preliminary study was undertaken to identify new human leucocyte antigens (HLA) ligands from human immunodeficiency virus type 1 (HIV-1) which are highly conserved across HIV-1 clades and which may serve to induce cross-reactive cytotoxic T lymphocytes (CTLs). EpiMatrix was used to predict putative ligands from HIV-1 for HLA-A2 and HLA-B27. Twenty-six peptides that were both likely to bind and also highly...
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