Prediction of well-conserved HIV-1 ligands using a matrix-based algorithm, EpiMatrix.

doi:10.1016/s0264-410x(98)00173-x

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Article

Prediction of well-conserved HIV-1 ligands using a matrix-based algorithm, EpiMatrix.

Vaccine - 1 Nov 1998

Schafer J R, Jesdale B M, George J A, Kouttab N M, De Groot A S

Abstract excerpt

This preliminary study was undertaken to identify new human leucocyte antigens (HLA) ligands from human immunodeficiency virus type 1 (HIV-1) which are highly conserved across HIV-1 clades and which may serve to induce cross-reactive cytotoxic T lymphocytes (CTLs). EpiMatrix was used to predict p...

Topics

Algorithms
Alleles
Conserved Sequence
Epitopes, T-Lymphocyte
HIV Antigens
HIV-1
HLA-A2 Antigen
HLA-B27 Antigen
Humans
Ligands
Oligopeptides
Predictive Value of Tests
T-Lymphocytes, Cytotoxic
Viral Proteins

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