Temperature-dependent regulation of a heterologous transcriptional activation domain fused to yeast heat shock transcription factor.

doi:10.1128/mcb.12.3.1021-1030.1992

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Temperature-dependent regulation of a heterologous transcriptional activation domain fused to yeast heat shock transcription factor.

Molecular and cellular biology - 1 Mar 1992

Bonner J J, Heyward S, Fackenthal D L

Abstract excerpt

The heat shock transcription factor (HSF) of the yeast Saccharomyces cerevisiae is posttranslationally modified. At low growth temperatures, it activates transcription of heat shock genes only poorly; after shift to high temperatures, it activates transcription readily. In an effort to elucidate the mechanism of this regulation, we constructed a series of HSF-VP16 fusions that join the HSF DNA-binding domain to...

Topics

Base Sequence
Binding Sites
Cloning, Molecular
DNA, Fungal
DNA-Binding Proteins
Fungal Proteins
Gene Expression Regulation, Fungal
Heat-Shock Proteins
Immunoblotting
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Polymerase Chain Reaction

Protein Processing, Post-Translational

Recombinant Fusion Proteins

Restriction Mapping

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1545786
DOI: 10.1128/mcb.12.3.1021-1030.1992
PMCID: PMC369534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1545786-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temperature-dependent regulation of a heterologous transcriptional activation domain fused to yeast heat shock transcription factor.PMID 1545786Read ↗

Mutated yeast heat shock transcription factor activates transcription independently of hyperphosphorylation.Semantic proximity Read ↗

The DNA-binding domain of yeast Hsf1 regulates both DNA-binding and transcriptional activities.Semantic proximity Read ↗

The DNA-binding domain of yeast heat shock transcription factor independently regulates both the N- and C-terminal activation domains.Semantic proximity Read ↗

A Heat Shock-Responsive Domain of Human HSF1 That Regulates Transcription Activation Domain FunctionSemantic proximity Read ↗

Identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in Saccharomyces cerevisiae.Semantic proximity Read ↗

Phosphorylation of the yeast heat shock transcription factor is implicated in gene-specific activation dependent on the architecture of the heat shock element.Semantic proximity Read ↗

Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock.Semantic proximity Read ↗

Mutations in the Schizosaccharomyces pombe heat shock factor that differentially affect responses to heat and cadmium stress.Semantic proximity Read ↗

ASF1 and the SWI/SNF complex interact functionally during nucleosome displacement, while FACT is required for nucleosome reassembly at yeast heat shock gene promoters during sustained stress.Semantic proximity Read ↗

The function and regulation of heat shock transcription factor in CryptococcusSemantic proximity Read ↗

Mutational analysis of human heat-shock transcription factor 1 reveals a regulatory role for oligomerization in DNA-binding specificity.Semantic proximity Read ↗

Differential recognition of heat shock elements by members of the heat shock transcription factor family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.