Article
Cryptorchidism in LhrKO animals and the effect of testosterone-replacement therapy.
Human reproduction (Oxford, England) - 1 Apr 2006
Yuan F P, Lin D X, Rao C V, Lei Z M
Abstract excerpt
BACKGROUND: The objective of the current study was to characterize the morphological and genetic basis of cryptorchidism. METHODS AND RESULTS: We investigated cryptorchidism in LH receptor (Lhr) knockout (LhrKO) mice and how testosterone-replacement therapy (TRT) worked to correct the phenotype. The results revealed that while gubernacular development was indistinguishable between Lhr-null and wild-type animals...
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