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Article

The LQLP calcineurin docking site is a major determinant of the calcium-dependent activation of human TRESK background K+ channel.

The Journal of biological chemistry - 24 Oct 2014

Czirják Gábor, Enyedi Péter

Abstract excerpt

Calcium-dependent activation of human TRESK (TWIK-related spinal cord K(+) channel, K2P18.1) depends on direct targeting of calcineurin to the PQIIIS motif. In the present study we demonstrate that TRESK also contains another functionally relevant docking site for the phosphatase, the LQLP amino...

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Identifiers

PMID: 25202008
DOI: 10.1074/jbc.M114.577684
PMCID: PMC4207969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25202008-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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