Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between the PTPN22 +1858 C/T polymorphism and psoriatic arthritis.

Arthritis research & therapy - 16 Mar 2011

Juneblad Kristina, Johansson Martin, Rantapää-Dahlqvist Solbritt, Alenius Gerd-Marie

Abstract excerpt

INTRODUCTION: The purpose of the present study was to investigate the frequency of the PTPN22 +1858 C/T single nucleotide polymorphism (SNP) (rs 2476601), previously shown to be associated with several autoimmune diseases, in patients with psoriatic arthritis (PsA) in comparison with population based controls. METHODS: A total of 291 patients (145 male/146 female, mean age (± S.D.) 52.2 (± 13.1) years) with PsA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Psoriatic
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PTPN22 gene

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Source

Open in PubMed Open full text

Identifiers

PMID: 21410964
DOI: 10.1186/ar3284
PMCID: PMC3132030

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between the PTPN22 +1858 C/T polymorphism and psoriatic arthritis.PMID 21410964Read ↗

PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus.Semantic proximity Read ↗

PTPN22 C1858T and the risk of psoriasis: a meta-analysis.Semantic proximity Read ↗

Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients.Semantic proximity Read ↗

Association between inflammasome-related polymorphisms and psoriatic arthritis.Semantic proximity Read ↗

Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus.Semantic proximity Read ↗

Clinical and immunogenetic characterization in psoriatic arthritis patients.Semantic proximity Read ↗

Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study.Semantic proximity Read ↗

Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene.Semantic proximity Read ↗

Polymorphisms in the PTPN22 region are associated with psoriasis of early onset.Semantic proximity Read ↗

Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis.Semantic proximity Read ↗

The PTPN22 C1858T variant as a risk factor for rheumatoid arthritis and systemic lupus erythematosus but not for systemic sclerosis in the Colombian population.Semantic proximity Read ↗

Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.