Article
Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22.
The Journal of investigative dermatology - 1 Mar 2009
Li Yonghong, Liao Wilson, Chang Monica, Schrodi Steven J, Bui Nam, Catanese Joseph J, Poon Annie, Matsunami Nori, Callis-Duffin Kristina P, Leppert Mark F, Bowcock Anne M, Kwok Pui-Yan, Krueger Gerald G, Begovich Ann B
Abstract excerpt
Predisposition to psoriasis is known to be affected by genetic variation in HLA-C, IL12B, and IL23R, and although other psoriasis-associated variants have been identified, incontrovertible statistical evidence for these markers has not yet been obtained. To help resolve this issue, we tested 15 single-nucleotide polymorphisms (SNPs) from 7 putative psoriasis-risk genes in 1,448 psoriasis patients and 1,385...
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