Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retroviruses that express different ras mutants cause different types of tumors in chickens.

Oncogene - 1 Jan 1992

Givol I, Greenhouse J J, Hughes S H, Ewert D L

Abstract excerpt

We have used replication-competent retroviral vectors to express avian and murine ras genes in cultured chick embryo fibroblasts (CEF) and in chickens. Since the viral vectors are identical, it is possible to compare the oncogenic potential of the ras genes directly. The normal (12 gly) form of chicken c-Ha-ras is not oncogenic in vivo, nor does high-level expression transform CEF. Expression of murine v-ras or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transformation, Viral
Share to Chickens
Share to Genes, ras

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation

Share to Neoplasms, Experimental

Share to Retroviridae

Share to Transfection

Source

Identifiers

PMID: 1632878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retroviruses that express different ras mutants cause different types of tumors in chickens.PMID 1632878Read ↗

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences.Semantic proximity Read ↗

Transformation of chicken embryo fibroblast cells by avian retroviruses containing the human Fyn gene and its mutated genes.Semantic proximity Read ↗

Novel phenotype of C3H 10T1/2 fibroblasts cotransfected with the c-Ha-ras and adenovirus 5 E1A oncogenes.Semantic proximity Read ↗

Mutations within the 5' half of the avian retrovirus MC29 v-myc gene alter or abolish transformation of chicken embryo fibroblasts and macrophages.Semantic proximity Read ↗

Induction of proliferation or transformation of neuroretina cells by the mil and myc viral oncogenes.Semantic proximity Read ↗

Retention of oncogenicity by a Marek's disease virus mutant lacking six unique short region genesSemantic proximity Read ↗

Induction and progression of the transformed phenotype in cloned rat embryo fibroblast cells: studies employing type 5 adenovirus and wild-type and mutant Ha-ras oncogenes.Semantic proximity Read ↗

Neoplastic transformation and tumorigenesis by the human protooncogene MYC.Semantic proximity Read ↗

Growth characteristics of fowl adenovirus type 8 in a chicken hepatoma cell lineSemantic proximity Read ↗

Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities.Semantic proximity Read ↗

Phenotypic changes induced by wild type and variant c-src genes carrying C-terminal sequence alterations.Semantic proximity Read ↗

Unmutated proto-src coding region is tumorigenic if expressed from the promoter of Rous sarcoma virus: implications for the gene-mutation hypothesis of cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.