Article
Induction of the myofibroblast phenotype following elastolytic injury to mouse lung.
Histochemistry and cell biology - 1 May 2006
Rishikof David C, Lucey Edgar C, Kuang Ping-Ping, Snider Gordon L, Goldstein Ronald H
Abstract excerpt
The repair of alveolar structures following endotracheal administration of porcine pancreatic elastase (PPE) to mice involves the coordinated deposition of new matrix elements. We determined the induction of the myofibroblast phenotype following elastolytic injury to mouse lung by examining the expression of alpha-smooth muscle actin (alpha-SMA) by immunohistochemistry. We also examined elastin and alpha1(I)...
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