Article
Identification of cellular processes that are rapidly modulated in response to tracheal occlusion within mice lungs.
Pediatric research - 1 Feb 2008
Seaborn Tommy, St-Amand Jonny, Cloutier Marc, Tremblay Michel G, Maltais France, Dinel Stéphanie, Moulin Véronique, Khan Paul A, Piedboeuf Bruno
Abstract excerpt
Lung development progresses through a process reliant on mechanical cell stretch. However, this process is not well defined at the molecular level. Our goal was to globally analyze the transcriptome of fetal mouse lungs following short periods of tracheal occlusion (TO) to identify cellular processes that are rapidly modulated in response to intraluminal stretch increase. Serial analysis of gene expression (SAGE)...
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