Article
Impaired distal airway development in mice lacking elastin.
American journal of respiratory cell and molecular biology - 1 Sept 2000
Wendel D P, Taylor D G, Albertine K H, Keating M T, Li D Y
Abstract excerpt
Elastin is a major component of the mammalian lung, predominantly found in the alveoli. Destruction of alveolar elastic fibers is implicated in the pathogenic mechanism of emphysema in adults. These data define a role for elastin in the structure and function of the mature lung, and suggest that...
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