Article
ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin.
eNeuro - 1 Jan 2000
Hara Yoshinobu, Fukaya Masahiro, Hayashi Kanehiro, Kawauchi Takeshi, Nakajima Kazunori, Sakagami Hiroyuki
Abstract excerpt
During neural development, endosomal trafficking controls cell shape and motility through the polarized transport of membrane proteins related to cell-cell and cell-extracellular matrix interactions. ADP ribosylation factor 6 (Arf6) is a critical small GTPase that regulates membrane trafficking between the plasma membrane and endosomes. We herein demonstrated that the knockdown of endogenous Arf6 in mouse...
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