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Article

Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians.

BMC medical genetics - 2 Dec 2005

Dolan Ciara, Shields Denis C, Stanton Alice, O'Brien Eoin, Lambert Deborah M, O'Brien John K, Treacy Eileen P

Abstract excerpt

BACKGROUND: The recessive disorder trimethylaminuria is caused by defects in the FMO3 gene, and may be associated with hypertension. We investigated whether common polymorphisms of the FMO3 gene confer an increased risk for elevated blood pressure and/or essential hypertension. METHODS: FMO3 genotypes (E158K, V257M, E308G) were determined in 387 healthy subjects with ambulatory systolic and diastolic blood...

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Source

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Identifiers

PMID: 16324215
DOI: 10.1186/1471-2350-6-41
PMCID: PMC1316875

Genes

FMO3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians.PMID 16324215Read ↗

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Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.Semantic proximity Read ↗

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