Article
Haplotype frequency distribution and linkage disequilibrium analysis of single nucleotide polymorphisms at the human FMO3 gene locus.
Biochemical genetics - 1 Oct 2006
Hao Da-Cheng, Sun Jie, Furnes Bjarte, Schlenk Daniel, Hou Zhen-Fang, Zhang Ya-Ping, Yang Sheng-Li, Yang Ling
Abstract excerpt
We analyzed flavin-containing monooxygenase 3 (FMO3) polymorphisms, haplotype structure, and linkage disequilibrium (LD) in 256 Han Chinese and 50 African-American individuals to compare their haplotype frequencies and LD with other world populations. For the Han Chinese, genotyping of three haplotype tag single nucleotide polymorphisms (E158K, V257M, and E308G) was performed by polymerase chain reaction...
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