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Article

Association of polymorphisms and haplotypes in the human growth hormone 1 (GH1) gene with breast cancer.

Endocrine-related cancer - 1 Dec 2005

Wagner K, Hemminki K, Israelsson E, Grzybowska E, Klaes R, Chen B, Butkiewicz D, Pamula J, Pekala W, Försti A

Abstract excerpt

The growth hormone 1 (GH1)/insulin-like growth factor I (IGF-I) axis plays an important role in the development of breast cancer. By binding to its receptor, GH1 stimulates the production of IGF-I and its binding protein IGFBP3, resulting in the regulation of cell proliferation, differentiation a...

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Source

Identifiers

PMID: 16322331
DOI: 10.1677/erc.1.01073

Genes

IGFBP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16322331-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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