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Article

The GH1/IGF-1 axis polymorphisms and their impact on breast cancer development.

Breast cancer research and treatment - 1 Sept 2007

Wagner Kerstin, Hemminki Kari, Försti Asta

Abstract excerpt

The growth hormone 1/insulin-like growth factor-1 (GH1/IGF-1) axis plays an essential role in the development of the breast by regulating cell proliferation, differentiation and apoptosis. Imbalances within this axis lead to an aberrant signalling and recent research has focussed on the overexpression of these growth factors and their involvement in breast cancer development. The increased understanding of the...

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Source

Identifiers

PMID: 17082888
DOI: 10.1007/s10549-006-9411-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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