Article
Polymorphism in genes of growth hormone receptor (GHR) and insulin-like growth factor-1 (IGF1) and its association with both the IGF1 expression in liver and its level in blood in Polish Holstein-Friesian cattle.
Neuro endocrinology letters - 1 Dec 2008
Maj Andrzej, Snochowski Marek, Siadkowska Eulalia, Rowinska Barbara, Lisowski Pawel, Robakowska-Hyzorek Dagmara, Oprzadek Jolanta, Grochowska Renata, Kochman Kazimierz, Zwierzchowski Lech
Abstract excerpt
BACKGROUND: Polymorphisms in the bovine ghr and igf1 genes. Ghr and igf1 genes have been associated with milk and meat production of cattle. However, the molecular and physiological mechanisms underlying such associations are unknown. The objective of this study was to examine the effects of polymorphisms in 5'-regions of the bovine ghr and igf1 genes on the igf1 gene expression in the liver and on the level of...
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