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Matrix Metalloproteinases in Helicobacter pylori–Associated Gastritis and Gastric Cancer

8 Feb 2022

Abstract excerpt

Gastric cancer is one of the leading causes of the cancer-related mortality worldwide. The etiology of this disease is complex and involves genetic predisposition and environmental factors, including Helicobacter pylori. Infection of the stomach with H. pylori leads to gastritis and gastric atrophy, which can progress stepwise to gastric cancer. Matrix metalloproteinases (MMPs) actively participate in the...

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PMID: 35163805
DOI: 10.3390/ijms23031883

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